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Integrin-linked kinase is responsible for Ca(2+)-independent myosin diphosphorylation and contraction of vascular smooth muscle
Smooth muscle contraction is activated by phosphorylation at Ser-19 of LC(20) (the 20 kDa light chains of myosin II) by Ca(2+)/calmodulin-dependent MLCK (myosin light-chain kinase). Diphosphorylation of LC(20) at Ser-19 and Thr-18 is observed in smooth muscle tissues and cultured cells in response t...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Portland Press Ltd.
2005
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1316305/ https://ncbi.nlm.nih.gov/pubmed/16201970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051173 |
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