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Pharmacophore and Molecular Docking Guided 3D-QSAR Study of Bacterial Enoyl-ACP Reductase (FabI) Inhibitors

Enoyl acyl carrier protein (ACP) reductase (FabI) is a potential target for the development of antibacterial agents. Three-dimensional quantitative structure-activity relationships (3D-QSAR) for substituted formamides series of FabI inhibitors were investigated using comparative molecular field anal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lu, Xiaoyun, Lv, Man, Huang, Kun, Ding, Ke, You, Qidong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Molecular Diversity Preservation International (MDPI) 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397485/
https://ncbi.nlm.nih.gov/pubmed/22837653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13066620
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