Pharmacophore and Molecular Docking Guided 3D-QSAR Study of Bacterial Enoyl-ACP Reductase (FabI) Inhibitors

Por Lu, Xiaoyun, Lv, Man, Huang, Kun, Ding, Ke, You, Qidong
Publicado em 2012

Improving the catalytic activity of isopentenyl phosphate kinase through protein coevolution analysis

Por Liu, Ying, Yan, Zhihui, Lu, Xiaoyun, Xiao, Dongguang, Jiang, Huifeng
Publicado no Sci Rep (2016)

Synthesis and identification of GZD856 as an orally bioavailable Bcr-Abl(T315I) inhibitor overcoming acquired imatinib resistance

Por Lu, Xiaoyun, Zhang, Zhang, Ren, Xiaomei, Wang, Deping, Ding, Ke
Publicado no J Enzyme Inhib Med Chem (2017)

Crystallization and preliminary X-ray analysis of an alanine dehydrogenase from Bacillus megaterium WSH-002

Por Lu, Xiaoyun, Yi, Qiufen, Zhang, Guofang, Zhu, Xianming, Zhou, Honggang, Dong, Hui
Publicado em 2013

Crystallization and preliminary X-ray analysis of an alanine dehydrogenase from Bacillus megaterium WSH-002. Corrigendum

Por Lu, Xiaoyun, Yi, Qiufen, Zhang, Guofang, Zhu, Xianming, Zhou, Honggang, Dong, Hui
Publicado em 2013

Crystallization and preliminary X-ray study of a thermostable alanine racemase from Thermoanaerobacter tengcongensis MB4

Por Dong, Hui, Xu, Shujing, Lu, Xiaoyun, He, Guangzheng, Zhao, Ranran, Chen, Shuai, Fu, Sheng, Ju, Jiansong
Publicado em 2013

Crystallization and preliminary X-ray study of a thermostable alanine racemase from Thermoanaerobacter tengcongensis MB4. Corrigendum

Por Dong, Hui, Xu, Shujing, Lu, Xiaoyun, He, Guangzheng, Zhao, Ranran, Chen, Shuai, Fu, Sheng, Ju, Jiansong
Publicado em 2013

Construction of energy-conserving sucrose utilization pathways for improving poly-γ-glutamic acid production in Bacillus amyloliquefaciens

Por Feng, Jun, Gu, Yanyan, Quan, Yufen, Gao, Weixia, Dang, Yulei, Cao, Mingfeng, Lu, Xiaoyun, Wang, Yi, Song, Cunjiang, Wang, Shufang
Publicado no Microb Cell Fact (2017)

YL143, a novel mutant selective irreversible EGFR inhibitor, overcomes EGFR(L858R, T790M)‐mutant resistance in vitro and in vivo

Por Zhang, Zhang, Zou, Jian, Yu, Lei, Luo, Jinfeng, Li, Yan, Tu, Zhengchao, Ren, Xiaomei, Wei, Hongcheng, Song, Liyan, Lu, Xiaoyun, Ding, Ke
Publicado no Cancer Med (2018)

Design, Synthesis, and Biological Evaluation of Pyrazolo[1,5-a]pyridine-3-carboxamides as Novel Antitubercular Agents

Por Tang, Jian, Wang, Bangxing, Wu, Tian, Wan, Junting, Tu, Zhengchao, Njire, Moses, Wan, Baojie, Franzblauc, Scott G., Zhang, Tianyu, Lu, Xiaoyun, Ding, Ke
Publicado no ACS Med Chem Lett (2015)

Alkylating agent melphalan augments the efficacy of adoptive immunotherapy using tumor-specific CD4(+) T cells

Por Lu, Xiaoyun, Ding, Zhi-Chun, Cao, Yang, Liu, Chufeng, Habtetsion, Tsadik, Yu, Miao, Lemos, Henrique, Salman, Huda, Xu, Hongyan, Mellor, Andrew L., Zhou, Gang
Publicado no J Immunol (2015)

Enhancing poly-γ-glutamic acid production in Bacillus amyloliquefaciens by introducing the glutamate synthesis features from Corynebacterium glutamicum

Por Feng, Jun, Quan, Yufen, Gu, Yanyan, Liu, Fenghong, Huang, Xiaozhong, Shen, Haosheng, Dang, Yulei, Cao, Mingfeng, Gao, Weixia, Lu, Xiaoyun, Wang, Yi, Song, Cunjiang, Wang, Shufang
Publicado no Microb Cell Fact (2017)

2-Aminopyrimidine Derivatives as New Selective Fibroblast Growth Factor Receptor 4 (FGFR4) Inhibitors

Por Mo, Cheng, Zhang, Zhang, Guise, Christopher P., Li, Xueqiang, Luo, Jinfeng, Tu, Zhengchao, Xu, Yong, Patterson, Adam V., Smaill, Jeff B., Ren, Xiaomei, Lu, Xiaoyun, Ding, Ke
Publicado no ACS Med Chem Lett (2017)

HOTAIR rs7958904 polymorphism is associated with increased cervical cancer risk in a Chinese population

Por Jin, Hua, Lu, Xiaoyun, Ni, Jing, Sun, Jinfang, Gu, Bin, Ding, Bo, Zhu, Haixia, Ma, Chao, Cui, Mengjing, Xu, Yuling, Zhang, Zhengdong, Lercher, Martin, Chen, Jian, Gao, Na, Wang, Shizhi
Publicado no Sci Rep (2017)

Essential Role of the p110β Subunit of Phosphoinositide 3-OH Kinase in Male Fertility

Por Ciraolo, Elisa, Morello, Fulvio, Hobbs, Robin M., Wolf, Frieder, Marone, Romina, Iezzi, Manuela, Lu, Xiaoyun, Mengozzi, Giulio, Altruda, Fiorella, Sorba, Giovanni, Guan, Kaomei, Pandolfi, Pier Paolo, Wymann, Matthias P., Hirsch, Emilio
Publicado em 2010

Tetrahydroisoquinoline-7-carboxamide Derivatives as New Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors

Por Wang, Zhen, Zhang, Yali, Bartual, Sergio G., Luo, Jinfeng, Xu, Tingting, Du, Wenting, Xun, Qiuju, Tu, Zhengchao, Brekken, Rolf A., Ren, Xiaomei, Bullock, Alex N., Liang, Guang, Lu, Xiaoyun, Ding, Ke
Publicado no ACS Med Chem Lett (2017)

Immunosuppressive myeloid cells induced by chemotherapy attenuate antitumor CD4+ T cell responses through the PD-1/PD-L1 axis

Por Ding, Zhi-Chun, Lu, Xiaoyun, Yu, Miao, Lemos, Henrique, Huang, Lei, Chandler, Phillip, Liu, Kebin, Walters, Matthew, Krasinski, Antoni, Mack, Matthias, Blazar, Bruce R., Mellor, Andrew L., Munn, David H., Zhou, Gang
Publicado em 2014

Structure-Based Design of Tetrahydroisoquinoline-7-carboxamides as Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors

Por Wang, Zhen, Bian, Huan, Bartual, Sergio G., Du, Wenting, Luo, Jinfeng, Zhao, Hu, Zhang, Shasha, Mo, Cheng, Zhou, Yang, Xu, Yong, Tu, Zhengchao, Ren, Xiaomei, Lu, Xiaoyun, Brekken, Rolf A., Yao, Libo, Bullock, Alex N., Su, Jin, Ding, Ke
Publicado no J Med Chem (2016)

GZD824 suppresses the growth of human B cell precursor acute lymphoblastic leukemia cells by inhibiting the SRC kinase and PI3K/AKT pathways

Por Ye, Wei, Jiang, Zhiwu, Lu, Xiaoyun, Ren, Xiaomei, Deng, Manman, Lin, Shouheng, Xiao, Yiren, Lin, Simiao, Wang, Suna, Li, Baiheng, Zheng, Yi, Lai, Peilong, Weng, Jianyu, Wu, Donghai, Ma, Yuguo, Chen, Xudong, Wen, Zhesheng, Chen, Yaoyu, Feng, Xiaoyan, Li, Yangqiu, Liu, Pentao, Du, Xin, Pei, Duanqing, Yao, Yao, Xu, Bing, Ding, Ke, Li, Peng
Publicado no Oncotarget (2016)

Evaluation of Aminohydantoins as a Novel Class of Antimalarial Agents

Por Meyers, Marvin J., Tortorella, Micky D., Xu, Jing, Qin, Limei, He, Zhengxiang, Lang, Xingfen, Zeng, Wentian, Xu, Wanwan, Qin, Li, Prinsen, Michael J., Sverdrup, Francis M., Eickhoff, Christopher S., Griggs, David W., Oliva, Jonathan, Ruminski, Peter G., Jacobsen, E. Jon, Campbell, Mary A., Wood, David C., Goldberg, Daniel E., Liu, Xiaorong, Lu, Yongzhi, Lu, Xin, Tu, Zhengchao, Lu, Xiaoyun, Ding, Ke, Chen, Xiaoping
Publicado em 2013