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Autoimmune Epididymo-orchitis is Essential to the Pathogenesis of Male-Specific Spondyloarthritis in HLA-B27 Transgenic Rats
OBJECTIVE: Male rats transgenic for HLA-B27 and human-β2-microglobulin (Hu-β2m) spontaneously develop epididymo-orchitis preceding spondyloarthritis. In the specific B27/Hu-β2m transgenic cross (21-3x382-2)F1, only the males develop spondyloarthritis, and neither sex develops gut inflammation. We as...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3396784/ https://ncbi.nlm.nih.gov/pubmed/22488218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.34480 |
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