Autoimmune Epididymo-orchitis is Essential to the Pathogenesis of Male-Specific Spondyloarthritis in HLA-B27 Transgenic Rats

OBJECTIVE: Male rats transgenic for HLA-B27 and human-β2-microglobulin (Hu-β2m) spontaneously develop epididymo-orchitis preceding spondyloarthritis. In the specific B27/Hu-β2m transgenic cross (21-3x382-2)F1, only the males develop spondyloarthritis, and neither sex develops gut inflammation. We as...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Taurog, Joel D., Rival, Claudia, van Duivenvoorde, Leonie M., Satumtira, Nimman, Dorris, Martha L., Sun, Margaret, Shelton, John M., Richardson, James A., Hamra, F. Kent, Hammer, Robert E., Tung, Kenneth S. K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396784/
https://ncbi.nlm.nih.gov/pubmed/22488218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.34480
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