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Structure and permeation mechanism of a mammalian urea transporter

As an adaptation to infrequent access to water, terrestrial mammals produce urine that is hyperosmotic to plasma. To prevent osmotic diuresis by the large quantity of urea generated by protein catabolism, the kidney epithelia contain facilitative urea transporters (UTs) that allow rapid equilibratio...

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Détails bibliographiques
Auteurs principaux: Levin, Elena J., Cao, Yu, Enkavi, Giray, Quick, Matthias, Pan, Yaping, Tajkhorshid, Emad, Zhou, Ming
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396522/
https://ncbi.nlm.nih.gov/pubmed/22733730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207362109
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