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Simulation of Spontaneous Substrate Binding Revealing the Binding Pathway and Mechanism and Initial Conformational Response of GlpT

Glycerol-3-phosphate transporter (GlpT) mediates the import of glycerol-3-phosphate (G3P) using the gradient of inorganic phosphate (P(i)). In order to study the process and mechanism of substrate binding and to investigate the protein's initial response, equilibrium simulations of wild-type an...

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Bibliografiske detaljer
Main Authors: Enkavi, Giray, Tajkhorshid, Emad
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829668/
https://ncbi.nlm.nih.gov/pubmed/20058936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901412a
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