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Simulation of Spontaneous Substrate Binding Revealing the Binding Pathway and Mechanism and Initial Conformational Response of GlpT

Glycerol-3-phosphate transporter (GlpT) mediates the import of glycerol-3-phosphate (G3P) using the gradient of inorganic phosphate (P(i)). In order to study the process and mechanism of substrate binding and to investigate the protein's initial response, equilibrium simulations of wild-type an...

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Bibliographische Detailangaben
Hauptverfasser: Enkavi, Giray, Tajkhorshid, Emad
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2829668/
https://ncbi.nlm.nih.gov/pubmed/20058936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901412a
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