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Salt bridge dynamics control substrate-induced conformational change in the membrane transporter GlpT

Active transport of substrates across cytoplasmic membranes is of great physiological, medical and pharmaceutical importance. The glycerol-3-phosphate (G3P) transporter (GlpT) of the E. coli inner membrane is a secondary active antiporter from the ubiquitous major facilitator superfamily that couple...

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Detalhes bibliográficos
Main Authors: Law, Christopher J., Almqvist, Jonas, Bernstein, Adam, Goetz, Regina M., Huang, Yafei, Soudant, Celine, Laaksonen, Aatto, Hovmöller, Sven, Wang, Da-Neng
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2426824/
https://ncbi.nlm.nih.gov/pubmed/18395745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.03.029
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