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Docking and homology modeling explain inhibition of the human vesicular glutamate transporters
As membrane transporter proteins, VGLUT1–3 mediate the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. This function is crucial for exocytosis and the role of glutamate as the major excitatory neurotransmitter in the central nervous system. The t...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Wiley-Blackwell
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2206968/ https://ncbi.nlm.nih.gov/pubmed/17660252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.072944707 |
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