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Docking and homology modeling explain inhibition of the human vesicular glutamate transporters

As membrane transporter proteins, VGLUT1–3 mediate the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. This function is crucial for exocytosis and the role of glutamate as the major excitatory neurotransmitter in the central nervous system. The t...

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Autori principali: Almqvist, Jonas, Huang, Yafei, Laaksonen, Aatto, Wang, Da-Neng, Hovmöller, Sven
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley-Blackwell 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206968/
https://ncbi.nlm.nih.gov/pubmed/17660252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.072944707
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