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Crystal structure of a bacterial homolog of the kidney urea transporter

Urea is highly concentrated in mammalian kidney to produce the osmotic gradient necessary for water re-absorption. Free diffusion of urea across cell membranes is slow due to its high polarity, and specialized urea transporters have evolved to achieve rapid and selective urea permeation. Here we pre...

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Bibliografski detalji
Glavni autori: Levin, Elena J., Quick, Matthias, Zhou, Ming
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871279/
https://ncbi.nlm.nih.gov/pubmed/19865084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08558
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