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Crystal structure of a bacterial homolog of the kidney urea transporter
Urea is highly concentrated in mammalian kidney to produce the osmotic gradient necessary for water re-absorption. Free diffusion of urea across cell membranes is slow due to its high polarity, and specialized urea transporters have evolved to achieve rapid and selective urea permeation. Here we pre...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2871279/ https://ncbi.nlm.nih.gov/pubmed/19865084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08558 |
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