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Structural basis of the alternating-access mechanism in a bile acid transporter
Bile acids are synthesized from cholesterol in hepatocytes and secreted via the biliary tract into the small intestine, where they aid in absorption of lipids and fat-soluble vitamins. Through a process known as enterohepatic recirculation, more than 90% of secreted bile acids are then retrieved fro...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4142352/ https://ncbi.nlm.nih.gov/pubmed/24317697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12811 |
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