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Structure and permeation mechanism of a mammalian urea transporter

As an adaptation to infrequent access to water, terrestrial mammals produce urine that is hyperosmotic to plasma. To prevent osmotic diuresis by the large quantity of urea generated by protein catabolism, the kidney epithelia contain facilitative urea transporters (UTs) that allow rapid equilibratio...

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Detalhes bibliográficos
Main Authors: Levin, Elena J., Cao, Yu, Enkavi, Giray, Quick, Matthias, Pan, Yaping, Tajkhorshid, Emad, Zhou, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396522/
https://ncbi.nlm.nih.gov/pubmed/22733730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207362109
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