Disturbed brain phospholipid and docosahexaenoic acid metabolism in calcium-independent phospholipase A(2)-VIA (iPLA(2)β)-knockout mice

Calcium-independent phospholipase A(2) group VIA (iPLA(2)β) releases docosahexaenoic acid (DHA) from phospholipids in vitro. Mutations in the iPLA(2)β gene, PLA2G6, are associated with dystonia-parkinsonism and infantile neuroaxonal dystrophy. To understand the role of iPLA(2)β in brain, we applied...

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Autori principali: Cheon, Yewon, Kim, Hyung-Wook, Igarashi, Miki, Modi, Hiren R., Chang, Lisa, Ma, Kaizong, Greenstein, Deanna, Wohltmann, Mary, Turk, John, Rapoport, Stanley I, Taha, Ameer Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393806/
https://ncbi.nlm.nih.gov/pubmed/22349267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2012.02.003
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