Imaging decreased brain docosahexaenoic acid metabolism and signaling in iPLA(2)β (VIA)-deficient mice

Ca(2+)-independent phospholipase A(2)β (iPLA(2)β) selectively hydrolyzes docosahexaenoic acid (DHA, 22:6n-3) in vitro from phospholipid. Mutations in the PLA2G6 gene encoding this enzyme occur in patients with idiopathic neurodegeneration plus brain iron accumulation and dystonia-parkinsonism withou...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Basselin, Mireille, Rosa, Angelo O., Ramadan, Epolia, Cheon, Yewon, Chang, Lisa, Chen, Mei, Greenstein, Deanna, Wohltmann, Mary, Turk, John, Rapoport, Stanley I.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952557/
https://ncbi.nlm.nih.gov/pubmed/20686114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M008334
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares