Polarization of Macrophages toward M2 Phenotype Is Favored by Reduction in iPLA(2)β (Group VIA Phospholipase A(2))

Macrophages are important in innate and adaptive immunity. Macrophage participation in inflammation or tissue repair is directed by various extracellular signals and mediated by multiple intracellular pathways. Activation of group VIA phospholipase A(2) (iPLA(2)β) causes accumulation of arachidonic...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ashley, Jason W., Hancock, William D., Nelson, Alexander J., Bone, Robert N., Tse, Hubert M., Wohltmann, Mary, Turk, John, Ramanadham, Sasanka
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087743/
https://ncbi.nlm.nih.gov/pubmed/27650501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.754945
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