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Systematic Analysis of Metallo-β-Lactamases Using an Automated Database

Metallo-β-lactamases (MBLs) are enzymes that hydrolyze β-lactam antibiotics, resulting in bacterial resistance to these drugs. These proteins have caused concerns due to their facile transference, broad substrate spectra, and the absence of clinically useful inhibitors. To facilitate the classificat...

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Библиографические подробности
Главные авторы: Widmann, Michael, Pleiss, Jürgen, Oelschlaeger, Peter
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393435/
https://ncbi.nlm.nih.gov/pubmed/22547615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00255-12
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