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Systematic Analysis of Metallo-β-Lactamases Using an Automated Database

Metallo-β-lactamases (MBLs) are enzymes that hydrolyze β-lactam antibiotics, resulting in bacterial resistance to these drugs. These proteins have caused concerns due to their facile transference, broad substrate spectra, and the absence of clinically useful inhibitors. To facilitate the classificat...

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Detalhes bibliográficos
Main Authors: Widmann, Michael, Pleiss, Jürgen, Oelschlaeger, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393435/
https://ncbi.nlm.nih.gov/pubmed/22547615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00255-12
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