Aging Modulates Susceptibility to Mouse Liver Mallory-Denk Body Formation

Mallory-Denk bodies (MDBs) are hepatocyte cytoplasmic inclusions found in several liver diseases and consist primarily of the cytoskeletal proteins, keratins 8 and 18 (K8/K18). Recent evidence indicates that the extent of stress-induced protein misfolding, a K8>K18 overexpression state, and trans...

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Autori principali: Hanada, Shinichiro, Harada, Masaru, Abe, Mitsuhiko, Akiba, Jun, Sakata, Masahiro, Kwan, Raymond, Taniguchi, Eitaro, Kawaguchi, Takumi, Koga, Hironori, Nagata, Eisuke, Ueno, Takato, Sata, Michio
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2012
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393076/
https://ncbi.nlm.nih.gov/pubmed/22473941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155412441478
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