Pigment Epithelium-Derived Factor Inhibits Lysosomal Degradation of Bcl-xL and Apoptosis in HepG2 cells

Pigment epithelium-derived factor (PEDF) has several biological actions on tumor cells, but its effects are cell-type dependent. The aim of this study was to examine the pathophysiological role of PEDF in hepatocellular carcinoma (HCC). PEDF expression was examined in various hepatoma cell lines and...

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Detalhes bibliográficos
Main Authors: Kawaguchi, Takumi, Yamagishi, Sho-ichi, Itou, Minoru, Okuda, Koji, Sumie, Shuji, Kuromatsu, Ryoko, Sakata, Masahiro, Abe, Mitsuhiko, Taniguchi, Eitaro, Koga, Hironori, Harada, Masaru, Ueno, Takato, Sata, Michio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797879/
https://ncbi.nlm.nih.gov/pubmed/19948828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090242
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