The Wilson Disease Protein ATP7B Resides in the Late Endosomes with Rab7 and the Niemann-Pick C1 Protein

Wilson disease is a genetic disorder characterized by the accumulation of copper in the body due to a defect of biliary copper excretion. Although the Wilson disease gene has been cloned, the cellular localization of the gene product (ATP7B) has not been fully clarified. Therefore, the precise physi...

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Hlavní autoři: Harada, Masaru, Kawaguchi, Takumi, Kumemura, Hiroto, Terada, Kunihiko, Ninomiya, Haruaki, Taniguchi, Eitaro, Hanada, Shinichiro, Baba, Shinji, Maeyama, Michiko, Koga, Hironori, Ueno, Takato, Furuta, Koh, Suganuma, Tatsuo, Sugiyama, Toshihiro, Sata, Michio
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2005
Témata:
Original Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602322/
https://ncbi.nlm.nih.gov/pubmed/15681833
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