Hepatitis C Virus Down-Regulates Insulin Receptor Substrates 1 and 2 through Up-Regulation of Suppressor of Cytokine Signaling 3

The pathogenesis of hepatitis C virus (HCV)-associated insulin resistance remains unclear. Therefore, we investigated mechanisms for HCV-associated insulin resistance. Homeostasis model assessment for insulin resistance was increased in patients with HCV infection. An increase in fasting insulin lev...

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Main Authors: Kawaguchi, Takumi, Yoshida, Takafumi, Harada, Masaru, Hisamoto, Takao, Nagao, Yumiko, Ide, Tatsuya, Taniguchi, Eitaro, Kumemura, Hiroto, Hanada, Shinichiro, Maeyama, Michiko, Baba, Shinji, Koga, Hironori, Kumashiro, Ryukichi, Ueno, Takato, Ogata, Hisanobu, Yoshimura, Akihiko, Sata, Michio
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2004
Fag:
Original Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618659/
https://ncbi.nlm.nih.gov/pubmed/15509521
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