CR4056, a new analgesic I2 ligand, is highly effective against bortezomib-induced painful neuropathy in rats

Although bortezomib (BTZ) is the frontline treatment for multiple myeloma, its clinical use is limited by the occurrence of painful peripheral neuropathy, whose treatment is still an unmet clinical need. Previous studies have shown chronic BTZ administration (0.20 mg/kg intravenously three times a w...

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Detalhes bibliográficos
Principais autores: Meregalli, Cristina, Ceresa, Cecilia, Canta, Annalisa, Carozzi, Valentina Alda, Chiorazzi, Alessia, Sala, Barbara, Oggioni, Norberto, Lanza, Marco, Letari, Ornella, Ferrari, Flora, Avezza, Federica, Marmiroli, Paola, Caselli, GianFranco, Cavaletti, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392714/
https://ncbi.nlm.nih.gov/pubmed/22792002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S32122
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