Analgesic efficacy of CR4056, a novel imidazoline-2 receptor ligand, in rat models of inflammatory and neuropathic pain

Two decades of investigations have failed to unequivocally clarify the functions and the molecular nature of imidazoline-2 receptors (I2R). However, there is robust pharmacological evidence for the functional modulation of monoamino oxidase (MAO) and other important enzyme activities by I2 site liga...

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Bibliografiske detaljer
Main Authors: Ferrari, Flora, Fiorentino, Simonetta, Mennuni, Laura, Garofalo, Paolo, Letari, Ornella, Mandelli, Stefano, Giordani, Antonio, Lanza, Marco, Caselli, Gianfranco
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2011
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100226/
https://ncbi.nlm.nih.gov/pubmed/21647215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S18353
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