CR4056, a new analgesic I2 ligand, is highly effective against bortezomib-induced painful neuropathy in rats

Although bortezomib (BTZ) is the frontline treatment for multiple myeloma, its clinical use is limited by the occurrence of painful peripheral neuropathy, whose treatment is still an unmet clinical need. Previous studies have shown chronic BTZ administration (0.20 mg/kg intravenously three times a w...

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Détails bibliographiques
Auteurs principaux: Meregalli, Cristina, Ceresa, Cecilia, Canta, Annalisa, Carozzi, Valentina Alda, Chiorazzi, Alessia, Sala, Barbara, Oggioni, Norberto, Lanza, Marco, Letari, Ornella, Ferrari, Flora, Avezza, Federica, Marmiroli, Paola, Caselli, GianFranco, Cavaletti, Guido
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2012
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392714/
https://ncbi.nlm.nih.gov/pubmed/22792002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S32122
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