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CR4056, a new analgesic I2 ligand, is highly effective against bortezomib-induced painful neuropathy in rats

Although bortezomib (BTZ) is the frontline treatment for multiple myeloma, its clinical use is limited by the occurrence of painful peripheral neuropathy, whose treatment is still an unmet clinical need. Previous studies have shown chronic BTZ administration (0.20 mg/kg intravenously three times a w...

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Bibliografische gegevens
Hoofdauteurs: Meregalli, Cristina, Ceresa, Cecilia, Canta, Annalisa, Carozzi, Valentina Alda, Chiorazzi, Alessia, Sala, Barbara, Oggioni, Norberto, Lanza, Marco, Letari, Ornella, Ferrari, Flora, Avezza, Federica, Marmiroli, Paola, Caselli, GianFranco, Cavaletti, Guido
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove Medical Press 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392714/
https://ncbi.nlm.nih.gov/pubmed/22792002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S32122
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