CR4056, a new analgesic I2 ligand, is highly effective against bortezomib-induced painful neuropathy in rats

Although bortezomib (BTZ) is the frontline treatment for multiple myeloma, its clinical use is limited by the occurrence of painful peripheral neuropathy, whose treatment is still an unmet clinical need. Previous studies have shown chronic BTZ administration (0.20 mg/kg intravenously three times a w...

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Main Authors: Meregalli, Cristina, Ceresa, Cecilia, Canta, Annalisa, Carozzi, Valentina Alda, Chiorazzi, Alessia, Sala, Barbara, Oggioni, Norberto, Lanza, Marco, Letari, Ornella, Ferrari, Flora, Avezza, Federica, Marmiroli, Paola, Caselli, GianFranco, Cavaletti, Guido
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2012
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392714/
https://ncbi.nlm.nih.gov/pubmed/22792002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S32122
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