CR4056, a new analgesic I2 ligand, is highly effective against bortezomib-induced painful neuropathy in rats

Although bortezomib (BTZ) is the frontline treatment for multiple myeloma, its clinical use is limited by the occurrence of painful peripheral neuropathy, whose treatment is still an unmet clinical need. Previous studies have shown chronic BTZ administration (0.20 mg/kg intravenously three times a w...

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Autors principals: Meregalli, Cristina, Ceresa, Cecilia, Canta, Annalisa, Carozzi, Valentina Alda, Chiorazzi, Alessia, Sala, Barbara, Oggioni, Norberto, Lanza, Marco, Letari, Ornella, Ferrari, Flora, Avezza, Federica, Marmiroli, Paola, Caselli, GianFranco, Cavaletti, Guido
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2012
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392714/
https://ncbi.nlm.nih.gov/pubmed/22792002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S32122
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