()Autoreactive pre-plasma cells break tolerance in the absence of regulation by dendritic cells and macrophages

The ability to induce antibody responses to pathogens while maintaining the quiescence of autoreactive cells is an important aspect of immune tolerance. During activation of Toll-like receptor-4 (TLR4), dendritic cells (DCs) and macrophages (MFs) repress autoantibody production through their secreti...

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Detalhes bibliográficos
Main Authors: Gilbert, Mileka R., Wagner, Nikki J., Jones, Shannon Z., Wisz, Amanda B., Roques, Jose R., Krum, Kristen N., Lee, Sang-Ryul, Nickeleit, Volker, Hulbert, Chrys, Thomas, James W., Gauld, Stephen B., Vilen, Barbara J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392546/
https://ncbi.nlm.nih.gov/pubmed/22675201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102973
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