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Dendritic Cells from Lupus-Prone Mice Are Defective in Repressing Immunoglobulin Secretion

Autoimmunity results from a breakdown in tolerance mechanisms that regulate autoreactive lymphocytes. We recently showed that during innate immune responses, secretion of IL-6 by dendritic cells (DCs) maintained autoreactive B cells in an unresponsive state. In this study, we describe that TLR4-acti...

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Detalhes bibliográficos
Main Authors: Gilbert, Mileka R., Carnathan, Diane G., Cogswell, Patricia C., Lin, Li, Baldwin, Albert S., Vilen, Barbara J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700365/
https://ncbi.nlm.nih.gov/pubmed/17404261
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