Receptor cross-talk spatially restricts pERK during TLR4 stimulation of autoreactive B cells

To maintain tolerance, autoreactive B cells must regulate signal transduction from the B cell receptor and Toll-like receptors. We recently identified that dendritic cells and macrophages regulate autoreactive cells during TLR4 activation by releasing IL-6 and soluble CD40L (sCD40L). These cytokines...

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Detalhes bibliográficos
Main Authors: Lee, Sang-Ryul, Rutan, Jennifer A., Monteith, Andrew J., Jones, Shannon Z., Kang, Sun Ah, Krum, Kristen N., Kilmon, Michelle A., Roques, Jose R., Wagner, Nikki J., Clarke, Stephen H., Vilen, Barbara J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466401/
https://ncbi.nlm.nih.gov/pubmed/22984080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200940
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