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()Autoreactive pre-plasma cells break tolerance in the absence of regulation by dendritic cells and macrophages

The ability to induce antibody responses to pathogens while maintaining the quiescence of autoreactive cells is an important aspect of immune tolerance. During activation of Toll-like receptor-4 (TLR4), dendritic cells (DCs) and macrophages (MFs) repress autoantibody production through their secreti...

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書誌詳細
主要な著者: Gilbert, Mileka R., Wagner, Nikki J., Jones, Shannon Z., Wisz, Amanda B., Roques, Jose R., Krum, Kristen N., Lee, Sang-Ryul, Nickeleit, Volker, Hulbert, Chrys, Thomas, James W., Gauld, Stephen B., Vilen, Barbara J.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392546/
https://ncbi.nlm.nih.gov/pubmed/22675201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102973
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