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Inhibition of Mycobacterial Infection by the Tumor Suppressor PTEN

The tumor suppressor PTEN is a lipid phosphatase that is frequently mutated in various human cancers. PTEN suppresses tumor cell proliferation, survival, and growth mainly by inhibiting the PI3K-Akt signaling pathway through dephosphorylation of phosphatidylinositol 3,4,5-triphosphate. In addition t...

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Библиографические подробности
Главные авторы: Huang, Guochang, Redelman-Sidi, Gil, Rosen, Neal, Glickman, Michael S., Jiang, Xuejun
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391101/
https://ncbi.nlm.nih.gov/pubmed/22613768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.351940
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