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Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the PTEN tumor suppressor

The PTEN (phosphatase and tensin homologue) tumor suppressor protein contains a single catalytic domain with both lipid and protein phosphatase activities. The remaining C-terminal half of the PTEN protein plays a role in its stability and is mutated in many clinical cancer samples. Here, we report...

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Detalhes bibliográficos
Main Authors: Okumura, Koichi, Zhao, Mujun, DePinho, Ronald A., Furnari, Frank B., Cavenee, Webster K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC549467/
https://ncbi.nlm.nih.gov/pubmed/15659546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409370102
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