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Presenilins regulate the cellular level of the tumor suppressor PTEN

Alzheimer's disease (AD) is characterized by amyloid plaques consisting of β-amyloid (Aβ) peptides and neurofibrillary tangles consisting of hyperphosphorylated tau protein. Aβ is proteolytically derived from its precursor protein through cleavages by β-secretase and γ-secretase complex compris...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neurobiol Aging
Prif Awduron: Zhang, Han, Liu, Runzhong, Wang, Ruishan, Hong, Shuigen, Xu, Huaxi, Zhang, Yun-wu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405252/
https://ncbi.nlm.nih.gov/pubmed/17222949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2006.11.020
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