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Regulation of the tumor suppressor PTEN by SUMO

The crucial function of the PTEN tumor suppressor in multiple cellular processes suggests that its activity must be tightly controlled. Both, membrane association and a variety of post-translational modifications, such as acetylation, phosphorylation, and mono- and polyubiquitination, have been repo...

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Detalhes bibliográficos
Main Authors: González-Santamaría, J, Campagna, M, Ortega-Molina, A, Marcos-Villar, L, de la Cruz-Herrera, C F, González, D, Gallego, P, Lopitz-Otsoa, F, Esteban, M, Rodríguez, M S, Serrano, M, Rivas, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461367/
https://ncbi.nlm.nih.gov/pubmed/23013792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.135
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