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Regulation of Vaccinia Virus E3 Protein by Small Ubiquitin-Like Modifier Proteins

The vaccinia virus (VACV) E3 protein is essential for virulence and has antiapoptotic activity and the ability to impair the host innate immune response. Here we demonstrate that E3 interacts with SUMO1 through a small ubiquitin-like modifier (SUMO)-interacting motif (SIM). SIM integrity is required...

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Detalhes bibliográficos
Main Authors: González-Santamaría, José, Campagna, Michela, García, María Angel, Marcos-Villar, Laura, González, Dolores, Gallego, Pedro, Lopitz-Otsoa, Fernando, Guerra, Susana, Rodríguez, Manuel S., Esteban, Mariano, Rivas, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233166/
https://ncbi.nlm.nih.gov/pubmed/21957283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05628-11
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