Regulation of Vaccinia Virus E3 Protein by Small Ubiquitin-Like Modifier Proteins

The vaccinia virus (VACV) E3 protein is essential for virulence and has antiapoptotic activity and the ability to impair the host innate immune response. Here we demonstrate that E3 interacts with SUMO1 through a small ubiquitin-like modifier (SUMO)-interacting motif (SIM). SIM integrity is required...

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Hlavní autoři: González-Santamaría, José, Campagna, Michela, García, María Angel, Marcos-Villar, Laura, González, Dolores, Gallego, Pedro, Lopitz-Otsoa, Fernando, Guerra, Susana, Rodríguez, Manuel S., Esteban, Mariano, Rivas, Carmen
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233166/
https://ncbi.nlm.nih.gov/pubmed/21957283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05628-11
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