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Catalysis by the Tumor-Suppressor Enzymes PTEN and PTEN-L
Phosphatase and tensin homologue deleted from chromosome ten (PTEN) is a lipid phosphatase tumor suppressor that is lost or inactivated in most human tumors. The enzyme catalyzes the hydrolysis of phosphatidylinositol-(3,4,5)-trisphosphate (PIP(3)) to form phosphatidylinositol-(4,5)-bisphosphate (PI...
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| Publicado no: | PLoS One |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4301912/ https://ncbi.nlm.nih.gov/pubmed/25607987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116898 |
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