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Catalysis by the Tumor-Suppressor Enzymes PTEN and PTEN-L

Phosphatase and tensin homologue deleted from chromosome ten (PTEN) is a lipid phosphatase tumor suppressor that is lost or inactivated in most human tumors. The enzyme catalyzes the hydrolysis of phosphatidylinositol-(3,4,5)-trisphosphate (PIP(3)) to form phosphatidylinositol-(4,5)-bisphosphate (PI...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Johnston, Sean B., Raines, Ronald T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301912/
https://ncbi.nlm.nih.gov/pubmed/25607987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116898
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