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Inhibition of Mycobacterial Infection by the Tumor Suppressor PTEN
The tumor suppressor PTEN is a lipid phosphatase that is frequently mutated in various human cancers. PTEN suppresses tumor cell proliferation, survival, and growth mainly by inhibiting the PI3K-Akt signaling pathway through dephosphorylation of phosphatidylinositol 3,4,5-triphosphate. In addition t...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3391101/ https://ncbi.nlm.nih.gov/pubmed/22613768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.351940 |
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