Regulation of RAS oncogenicity by acetylation

Members of the RAS small GTPase family regulate cellular responses to extracellular stimuli by mediating the flux through downstream signal transduction cascades. RAS activity is strongly dependent on its subcellular localization and its nucleotide-binding status, both of which are modulated by post...

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Bibliographische Detailangaben
Hauptverfasser: Yang, Moon Hee, Nickerson, Seth, Kim, Eric T., Liot, Caroline, Laurent, Gaelle, Spang, Robert, Philips, Mark R., Shan, Yibing, Shaw, David E., Bar-Sagi, Dafna, Haigis, Marcia C., Haigis, Kevin M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390846/
https://ncbi.nlm.nih.gov/pubmed/22711838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201487109
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