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Regulation of RAS oncogenicity by acetylation

Members of the RAS small GTPase family regulate cellular responses to extracellular stimuli by mediating the flux through downstream signal transduction cascades. RAS activity is strongly dependent on its subcellular localization and its nucleotide-binding status, both of which are modulated by post...

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Detalhes bibliográficos
Main Authors: Yang, Moon Hee, Nickerson, Seth, Kim, Eric T., Liot, Caroline, Laurent, Gaelle, Spang, Robert, Philips, Mark R., Shan, Yibing, Shaw, David E., Bar-Sagi, Dafna, Haigis, Marcia C., Haigis, Kevin M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390846/
https://ncbi.nlm.nih.gov/pubmed/22711838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201487109
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