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Apoptotic and antitumor activity of death receptor antibodies require inhibitory Fcγ receptor engagement
By virtue of their ability to induce apoptosis and regulate growth, differentiation, and cytokine responses, the tumor necrosis factor receptor (TNFR) superfamily members have emerged as attractive targets for anticancer therapeutics. Agonistic antibodies to apoptosis-inducing TNFRs, such as death r...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3390832/ https://ncbi.nlm.nih.gov/pubmed/22723355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208698109 |
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