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Apoptotic and antitumor activity of death receptor antibodies require inhibitory Fcγ receptor engagement

By virtue of their ability to induce apoptosis and regulate growth, differentiation, and cytokine responses, the tumor necrosis factor receptor (TNFR) superfamily members have emerged as attractive targets for anticancer therapeutics. Agonistic antibodies to apoptosis-inducing TNFRs, such as death r...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Li, Fubin, Ravetch, Jeffrey V.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390832/
https://ncbi.nlm.nih.gov/pubmed/22723355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208698109
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