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Apoptotic and antitumor activity of death receptor antibodies require inhibitory Fcγ receptor engagement

By virtue of their ability to induce apoptosis and regulate growth, differentiation, and cytokine responses, the tumor necrosis factor receptor (TNFR) superfamily members have emerged as attractive targets for anticancer therapeutics. Agonistic antibodies to apoptosis-inducing TNFRs, such as death r...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Li, Fubin, Ravetch, Jeffrey V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390832/
https://ncbi.nlm.nih.gov/pubmed/22723355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208698109
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