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Endoproteolytic Cleavage of TUG Protein Regulates GLUT4 Glucose Transporter Translocation

To promote glucose uptake into fat and muscle cells, insulin causes the translocation of GLUT4 glucose transporters from intracellular vesicles to the cell surface. Previous data support a model in which TUG traps GLUT4-containing vesicles and tethers them intracellularly in unstimulated cells and i...

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Autors principals: Bogan, Jonathan S., Rubin, Bradley R., Yu, Chenfei, Löffler, Michael G., Orme, Charisse M., Belman, Jonathan P., McNally, Leah J., Hao, Mingming, Cresswell, James A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390669/
https://ncbi.nlm.nih.gov/pubmed/22610098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.339457
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