Acetylation of TUG Protein Promotes the Accumulation of GLUT4 Glucose Transporters in an Insulin-responsive Intracellular Compartment

Insulin causes the exocytic translocation of GLUT4 glucose transporters to stimulate glucose uptake in fat and muscle. Previous results support a model in which TUG traps GLUT4 in intracellular, insulin-responsive vesicles termed GLUT4 storage vesicles (GSVs). Insulin triggers TUG cleavage to releas...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Belman, Jonathan P., Bian, Rachel R., Habtemichael, Estifanos N., Li, Don T., Jurczak, Michael J., Alcázar-Román, Abel, McNally, Leah J., Shulman, Gerald I., Bogan, Jonathan S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2015
Onderwerpen:
Metabolism
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326849/
https://ncbi.nlm.nih.gov/pubmed/25561724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.603977
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