Acetylation of TUG Protein Promotes the Accumulation of GLUT4 Glucose Transporters in an Insulin-responsive Intracellular Compartment

Insulin causes the exocytic translocation of GLUT4 glucose transporters to stimulate glucose uptake in fat and muscle. Previous results support a model in which TUG traps GLUT4 in intracellular, insulin-responsive vesicles termed GLUT4 storage vesicles (GSVs). Insulin triggers TUG cleavage to releas...

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Vydáno v:J Biol Chem
Hlavní autoři: Belman, Jonathan P., Bian, Rachel R., Habtemichael, Estifanos N., Li, Don T., Jurczak, Michael J., Alcázar-Román, Abel, McNally, Leah J., Shulman, Gerald I., Bogan, Jonathan S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326849/
https://ncbi.nlm.nih.gov/pubmed/25561724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.603977
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