Endoproteolytic Cleavage of TUG Protein Regulates GLUT4 Glucose Transporter Translocation

To promote glucose uptake into fat and muscle cells, insulin causes the translocation of GLUT4 glucose transporters from intracellular vesicles to the cell surface. Previous data support a model in which TUG traps GLUT4-containing vesicles and tethers them intracellularly in unstimulated cells and i...

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Autori principali: Bogan, Jonathan S., Rubin, Bradley R., Yu, Chenfei, Löffler, Michael G., Orme, Charisse M., Belman, Jonathan P., McNally, Leah J., Hao, Mingming, Cresswell, James A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390669/
https://ncbi.nlm.nih.gov/pubmed/22610098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.339457
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