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THE GLUT4 REGULATING PROTEIN TUG IS ESSENTIAL FOR HIGHLY INSULIN RESPONSIVE GLUCOSE UPTAKE IN 3T3-L1 ADIPOCYTES

Insulin stimulates glucose uptake in fat and muscle by redistributing GLUT4 glucose transporters from intracellular membranes to the cell surface. We previously proposed that in 3T3-L1 adipocytes, TUG retains GLUT4 within unstimulated cells, and insulin mobilizes this retained GLUT4 by stimulating i...

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Detalhes bibliográficos
Main Authors: Yu, Chenfei, Cresswell, James, Löffler, Michael G., Bogan, Jonathan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2243252/
https://ncbi.nlm.nih.gov/pubmed/17202135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M610824200
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