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A Network of Ubiquitin Ligases Is Important for the Dynamics of Misfolded Protein Aggregates in Yeast

Quality control ubiquitin ligases promote degradation of misfolded proteins by the proteasome. If the capacity of the ubiquitin/proteasome system is exceeded, then misfolded proteins accumulate in aggregates that are cleared by the autophagic system. To identify components of the ubiquitin/proteasom...

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書誌詳細
主要な著者: Theodoraki, Maria A., Nillegoda, Nadinath B., Saini, Jagdeep, Caplan, Avrom J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390667/
https://ncbi.nlm.nih.gov/pubmed/22593585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.341164
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