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Colon Cancer-associated DNA Polymerase β Variant Induces Genomic Instability and Cellular Transformation
Rapidly advancing technology has resulted in the generation of the genomic sequences of several human tumors. We have identified several mutations of the DNA polymerase β (pol β) gene in human colorectal cancer. We have demonstrated that the expression of the pol β G231D variant increased chromosoma...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3390657/ https://ncbi.nlm.nih.gov/pubmed/22573322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.362111 |
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